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3l0h

From Proteopedia

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[[Image:3l0h.png|left|200px]]
 
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==Crystal Structure Analysis of W21A mutant of human GSTA1-1 in complex with S-hexylglutathione==
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The line below this paragraph, containing "STRUCTURE_3l0h", creates the "Structure Box" on the page.
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<StructureSection load='3l0h' size='340' side='right'caption='[[3l0h]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3l0h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L0H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTX:S-HEXYLGLUTATHIONE'>GTX</scene></td></tr>
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{{STRUCTURE_3l0h| PDB=3l0h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l0h OCA], [https://pdbe.org/3l0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l0h RCSB], [https://www.ebi.ac.uk/pdbsum/3l0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l0h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l0/3l0h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l0h ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure Analysis of W21A mutant of human GSTA1-1 in complex with S-hexylglutathione===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_20833278}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 20833278 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_20833278}}
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==About this Structure==
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[[3l0h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0H OCA].
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==Reference==
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<ref group="xtra">PMID:20833278</ref><references group="xtra"/>
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[[Category: Glutathione transferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Achilonu, I A.]]
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[[Category: Large Structures]]
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[[Category: Adamson, R J.]]
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[[Category: Achilonu IA]]
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[[Category: Burke, J P.]]
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[[Category: Adamson RJ]]
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[[Category: Dirr, H W.]]
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[[Category: Burke JP]]
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[[Category: Fanucchi, S.]]
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[[Category: Dirr HW]]
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[[Category: Fernandes, M A.]]
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[[Category: Fanucchi S]]
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[[Category: Fernandes MA]]

Current revision

Crystal Structure Analysis of W21A mutant of human GSTA1-1 in complex with S-hexylglutathione

PDB ID 3l0h

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