2z9n

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(New page: 200px<br /><applet load="2z9n" size="350" color="white" frame="true" align="right" spinBox="true" caption="2z9n, resolution 3.2&Aring;" /> '''Crystal structure of ...)
Current revision (08:08, 23 October 2024) (edit) (undo)
 
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[[Image:2z9n.gif|left|200px]]<br /><applet load="2z9n" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2z9n, resolution 3.2&Aring;" />
 
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'''Crystal structure of cameline peptidoglycan recognition protein at 3.2 A resolution'''<br />
 
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==About this Structure==
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==Crystal structure of cameline peptidoglycan recognition protein at 3.2 A resolution==
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2Z9N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] with <scene name='pdbligand=TLA:'>TLA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9N OCA].
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<StructureSection load='2z9n' size='340' side='right'caption='[[2z9n]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2z9n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z9N FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z9n OCA], [https://pdbe.org/2z9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z9n RCSB], [https://www.ebi.ac.uk/pdbsum/2z9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z9n ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/2z9n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z9n ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Jain, R.]]
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[[Category: Jain R]]
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[[Category: Kaur, P.]]
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[[Category: Kaur P]]
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[[Category: Sharma, P.]]
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[[Category: Sharma P]]
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[[Category: Sharma, S.]]
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[[Category: Sharma S]]
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[[Category: Singh, N.]]
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[[Category: Singh N]]
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[[Category: Singh, T.P.]]
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[[Category: Singh TP]]
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[[Category: TLA]]
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[[Category: antibiotic]]
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[[Category: antimicrobial]]
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[[Category: complex]]
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[[Category: crystal]]
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[[Category: immune response]]
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[[Category: peptidoglycan recognition protein]]
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[[Category: secreted]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:24:08 2008''
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Current revision

Crystal structure of cameline peptidoglycan recognition protein at 3.2 A resolution

PDB ID 2z9n

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