3q8e
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Protective Antigen W346F (pH 8.5)== | |
| - | + | <StructureSection load='3q8e' size='340' side='right'caption='[[3q8e]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3q8e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q8E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.098Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8e OCA], [https://pdbe.org/3q8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q8e RCSB], [https://www.ebi.ac.uk/pdbsum/3q8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q8e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus anthracis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Andra KK]] | ||
| + | [[Category: Bann JG]] | ||
| + | [[Category: Battaile KP]] | ||
| + | [[Category: Janowiak BE]] | ||
| + | [[Category: Lovell S]] | ||
| + | [[Category: Rajapaksha M]] | ||
Current revision
Crystal structure of Protective Antigen W346F (pH 8.5)
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