3q8x
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a toxin-antitoxin system bound to its substrate== | |
| - | + | <StructureSection load='3q8x' size='340' side='right'caption='[[3q8x]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3q8x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q8X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8x OCA], [https://pdbe.org/3q8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q8x RCSB], [https://www.ebi.ac.uk/pdbsum/3q8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q8x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EATX_STRPY EATX_STRPY] Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the toxic effect of cognate zeta toxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. Continuous synthesis of the epsilon antitoxin is required to counteract the zeta toxin.[REFERENCE:7] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptococcus pyogenes]] | ||
| + | [[Category: Gebhardt M]] | ||
| + | [[Category: Meinhart A]] | ||
| + | [[Category: Mutschler H]] | ||
| + | [[Category: Shoeman RL]] | ||
Current revision
Structure of a toxin-antitoxin system bound to its substrate
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