3q91
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)== | |
- | + | <StructureSection load='3q91' size='340' side='right'caption='[[3q91]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q91 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [https://pdbe.org/3q91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [https://www.ebi.ac.uk/pdbsum/3q91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q91 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Arrowsmith CH]] | ||
+ | [[Category: Berglund H]] | ||
+ | [[Category: Bountra C]] | ||
+ | [[Category: Collins R]] | ||
+ | [[Category: Edwards AM]] | ||
+ | [[Category: Ekblad T]] | ||
+ | [[Category: Flodin S]] | ||
+ | [[Category: Flores A]] | ||
+ | [[Category: Graslund S]] | ||
+ | [[Category: Hammarstrom M]] | ||
+ | [[Category: Johansson I]] | ||
+ | [[Category: Karlberg T]] | ||
+ | [[Category: Kol S]] | ||
+ | [[Category: Kotenyova T]] | ||
+ | [[Category: Kouznetsova E]] | ||
+ | [[Category: Moche M]] | ||
+ | [[Category: Nordlund P]] | ||
+ | [[Category: Nyman T]] | ||
+ | [[Category: Persson C]] | ||
+ | [[Category: Schuler H]] | ||
+ | [[Category: Schutz P]] | ||
+ | [[Category: Siponen MI]] | ||
+ | [[Category: Thorsell AG]] | ||
+ | [[Category: Tresaugues L]] | ||
+ | [[Category: Van Der Berg S]] | ||
+ | [[Category: Wahlberg E]] | ||
+ | [[Category: Weigelt J]] | ||
+ | [[Category: Welin M]] |
Current revision
Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berglund H | Bountra C | Collins R | Edwards AM | Ekblad T | Flodin S | Flores A | Graslund S | Hammarstrom M | Johansson I | Karlberg T | Kol S | Kotenyova T | Kouznetsova E | Moche M | Nordlund P | Nyman T | Persson C | Schuler H | Schutz P | Siponen MI | Thorsell AG | Tresaugues L | Van Der Berg S | Wahlberg E | Weigelt J | Welin M