3q91

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'''Unreleased structure'''
 
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The entry 3q91 is ON HOLD
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==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)==
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<StructureSection load='3q91' size='340' side='right'caption='[[3q91]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Tresaugues, L., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Thorsell, A.G., Van Der Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q91 FirstGlance]. <br>
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Description: Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [https://pdbe.org/3q91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [https://www.ebi.ac.uk/pdbsum/3q91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q91 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Berglund H]]
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[[Category: Bountra C]]
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[[Category: Collins R]]
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[[Category: Edwards AM]]
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[[Category: Ekblad T]]
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[[Category: Flodin S]]
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[[Category: Flores A]]
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[[Category: Graslund S]]
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[[Category: Hammarstrom M]]
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[[Category: Johansson I]]
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[[Category: Karlberg T]]
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[[Category: Kol S]]
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[[Category: Kotenyova T]]
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[[Category: Kouznetsova E]]
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[[Category: Moche M]]
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[[Category: Nordlund P]]
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[[Category: Nyman T]]
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[[Category: Persson C]]
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[[Category: Schuler H]]
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[[Category: Schutz P]]
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[[Category: Siponen MI]]
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[[Category: Thorsell AG]]
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[[Category: Tresaugues L]]
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[[Category: Van Der Berg S]]
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[[Category: Wahlberg E]]
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[[Category: Weigelt J]]
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[[Category: Welin M]]

Current revision

Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)

PDB ID 3q91

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