3opu

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[[Image:3opu.jpg|left|200px]]
 
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==Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP==
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The line below this paragraph, containing "STRUCTURE_3opu", creates the "Structure Box" on the page.
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<StructureSection load='3opu' size='340' side='right'caption='[[3opu]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3opu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.181&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_3opu| PDB=3opu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opu OCA], [https://pdbe.org/3opu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opu RCSB], [https://www.ebi.ac.uk/pdbsum/3opu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PAC_STRMG PAC_STRMG] Surface protein antigen implicated in dental caries.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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SpaP is a 1500-residue adhesin expressed on the surface of the caries-implicated bacterium Streptococcus mutans. SpaP is a member of the antigen I/II (AgI/II) family of proteins expressed by oral streptococci. These surface proteins are crucial for the incorporation of streptococci into dental plaque. The structure of the C-terminal domain of SpaP (residues 1136-1489) was solved and refined to 2.2 A resolution with six molecules in the asymmetric unit. Similar to a related AgI/II structure, SpaP is stabilized by isopeptide bonds between lysine and asparagine side chains.
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===Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP===
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Structure of the C-terminal domain of the surface antigen SpaP from the caries pathogen Streptococcus mutans.,Nylander A, Forsgren N, Persson K Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt, 1):23-6. Epub 2010 Dec 21. PMID:21206016<ref>PMID:21206016</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21206016}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3opu" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21206016 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21206016}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3opu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPU OCA].
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==Reference==
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<ref group="xtra">PMID:21206016</ref><references group="xtra"/>
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[[Category: Streptococcus mutans]]
[[Category: Streptococcus mutans]]
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[[Category: Nylander, A.]]
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[[Category: Nylander A]]
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[[Category: Persson, K.]]
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[[Category: Persson K]]

Current revision

Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP

PDB ID 3opu

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