3qdl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of RdxA from Helicobacter pyroli== | |
| + | <StructureSection load='3qdl' size='340' side='right'caption='[[3qdl]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3qdl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QDL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qdl OCA], [https://pdbe.org/3qdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qdl RCSB], [https://www.ebi.ac.uk/pdbsum/3qdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qdl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RDXA_HELPY RDXA_HELPY] Reduction of a variety of nitroaromatic compounds using NADPH as source of reducing equivalents; two electrons are transferred (By similarity). Capable of reducing metronidazole; inactive RdxA renders the bacterium resistant to this compound. The reduction of metronidazole generates hydroxylamine, a potent mutagen and bactericide.<ref>PMID:9622362</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Nitroreductase 3D structures|Nitroreductase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Helicobacter pylori]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hoffman PS]] | ||
| + | [[Category: Martinez-Julvez M]] | ||
| + | [[Category: Olekhnovich IN]] | ||
| + | [[Category: Rojas AL]] | ||
| + | [[Category: Sancho J]] | ||
Current revision
Crystal structure of RdxA from Helicobacter pyroli
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