2xzz
From Proteopedia
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| - | [[Image:2xzz.jpg|left|200px]] | ||
| - | + | ==Crystal structure of the human transglutaminase 1 beta-barrel domain== | |
| - | + | <StructureSection load='2xzz' size='340' side='right'caption='[[2xzz]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2xzz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XZZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzz OCA], [https://pdbe.org/2xzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xzz RCSB], [https://www.ebi.ac.uk/pdbsum/2xzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xzz ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | + | == Disease == | |
| - | === | + | [https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN] Lamellar ichthyosis;Self-healing collodion baby;Bathing suit ichthyosis;Acral self-healing collodion baby;Congenital non-bullous ichthyosiform erythroderma. The disease is caused by mutations affecting the gene represented in this entry. |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. | |
| - | == | + | __TOC__ |
| - | [[2xzz]] is a 1 chain structure with sequence from [ | + | </StructureSection> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Allerston | + | [[Category: Allerston C]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Chaikuad | + | [[Category: Chaikuad A]] |
| - | [[Category: Cooper | + | [[Category: Cooper C]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Kavanagh K]] |
| - | [[Category: Kavanagh | + | [[Category: Krojer T]] |
| - | [[Category: Krojer | + | [[Category: Krysztofinska E]] |
| - | [[Category: Krysztofinska | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Vollmar M]] |
| - | [[Category: Vollmar | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Yue WW]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
Current revision
Crystal structure of the human transglutaminase 1 beta-barrel domain
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Categories: Homo sapiens | Large Structures | Allerston C | Arrowsmith CH | Bountra C | Chaikuad A | Cooper C | Edwards A | Kavanagh K | Krojer T | Krysztofinska E | Oppermann U | Vollmar M | Weigelt J | Yue WW | Von Delft F
