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3qgb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3qgb is ON HOLD Authors: Wang, Y., Qiu, C., Koh, Y.Y., Opperman, L., Gross, L., Hall, T.M.T., Wickens, M. Description: Crystal structure of FBF-2 R...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa== | |
| - | + | <StructureSection load='3qgb' size='340' side='right'caption='[[3qgb]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3qgb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgb OCA], [https://pdbe.org/3qgb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgb RCSB], [https://www.ebi.ac.uk/pdbsum/3qgb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Caenorhabditis elegans]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gross L]] | ||
| + | [[Category: Hall TMT]] | ||
| + | [[Category: Koh YY]] | ||
| + | [[Category: Opperman L]] | ||
| + | [[Category: Qiu C]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Wickens M]] | ||
Current revision
Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa
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Categories: Caenorhabditis elegans | Large Structures | Gross L | Hall TMT | Koh YY | Opperman L | Qiu C | Wang Y | Wickens M
