3opf

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[[Image:3opf.jpg|left|200px]]
 
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==Crystal structure of TTHA0988 in space group P212121==
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The line below this paragraph, containing "STRUCTURE_3opf", creates the "Structure Box" on the page.
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<StructureSection load='3opf' size='340' side='right'caption='[[3opf]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3opf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3opf| PDB=3opf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opf OCA], [https://pdbe.org/3opf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opf RCSB], [https://www.ebi.ac.uk/pdbsum/3opf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SJM0_THET8 Q5SJM0_THET8]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The Thermus thermophilus protein TTHA0988 is a protein of unknown function which represents a fusion of two proteins found almost ubiquitously across the bacterial kingdom. These two proteins perform a role regulating sporulation in Bacillus subtilis, where they are known as KipI and KipA. kipI and kipA genes are usually found immediately adjacent to each other and are often fused to produce a single polypeptide, as is the case with TTHA0988. Here, three crystal forms are reported of TTHA0988, the first structure to be solved from the family of `KipI-KipA fusion' proteins. Comparison of the three forms reveals structural flexibility which can be described as a hinge motion between the `KipI' and `KipA' components. TTHA0988 is annotated in various databases as a putative allophanate hydrolase. However, no such activity could be identified and genetic analysis across species with known allophanate hydrolases indicates that a misannotation has occurred.
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===Crystal structure of TTHA0988 in space group P212121===
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The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase.,Jacques DA, Langley DB, Kuramitsu S, Yokoyama S, Trewhella J, Guss JM Acta Crystallogr D Biol Crystallogr. 2011 Feb;67(Pt 2):105-11. Epub 2011, Jan 8. PMID:21245531<ref>PMID:21245531</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3opf" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21245531 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21245531}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3opf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPF OCA].
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[[Category: Thermus thermophilus HB8]]
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[[Category: Guss JM]]
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==Reference==
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[[Category: Jacques DA]]
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<ref group="xtra">PMID:21245531</ref><references group="xtra"/>
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[[Category: Kuramitsu S]]
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[[Category: Thermus thermophilus]]
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[[Category: Trewhella J]]
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[[Category: Guss, J M.]]
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[[Category: Yokoyama S]]
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[[Category: Jacques, D A.]]
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[[Category: Kuramitsu, S.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Trewhella, J.]]
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[[Category: Yokoyama, S.]]
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Current revision

Crystal structure of TTHA0988 in space group P212121

PDB ID 3opf

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