2iod
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2iod" size="350" color="white" frame="true" align="right" spinBox="true" caption="2iod, resolution 2.060Å" /> '''Binding of two subs...) |
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| - | [[Image:2iod.jpg|left|200px]]<br /><applet load="2iod" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2iod, resolution 2.060Å" /> | ||
| - | '''Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site'''<br /> | ||
| - | == | + | ==Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site== |
| - | + | <StructureSection load='2iod' size='340' side='right'caption='[[2iod]], [[Resolution|resolution]] 2.06Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[Category: | + | <table><tr><td colspan='2'>[[2iod]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IOD FirstGlance]. <br> |
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYC:3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE'>MYC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iod OCA], [https://pdbe.org/2iod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iod RCSB], [https://www.ebi.ac.uk/pdbsum/2iod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iod ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DFRA_VITVI DFRA_VITVI] Bifunctional enzyme involved in flavonoid metabolism.[UniProtKB:Q9XES5] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2iod_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iod ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Vitis vinifera]] | [[Category: Vitis vinifera]] | ||
| - | + | [[Category: Gallois B]] | |
| - | [[Category: Gallois | + | [[Category: Granier T]] |
| - | [[Category: Granier | + | [[Category: Langlois d'Estaintot B]] |
| - | [[Category: | + | [[Category: Petit P]] |
| - | [[Category: | + | |
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Current revision
Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site
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