Ribosomal protein S6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:53, 1 March 2022) (edit) (undo)
 
(24 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:RPS6.png|left|200px|thumb|Crystal Structure of Ribosomal protein S6 from [[2zm6]], chain F]]
+
<StructureSection load='2bvz' size='350' side='right' scene='' caption='Ribosomal protein S6 (PDB code [[2bvz]])'>
-
{{STRUCTURE_2zm6| PDB=2zm6 | SIZE=300| SCENE=Ribosomal_protein_S6/Cv/1 |right|CAPTION=Ribosomal protein S6 from [[2zm6]], chain F }}
+
[[Ribosomal protein S6]] (RPS6) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S6/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It has a role in regulating translation of RNAs that contain the 5' terminal sequence<ref>PMID:16679021</ref>. It is regulated by ribosomal S6 kinase.
-
 
+
</StructureSection>
-
[[Ribosomal protein S6]] (RPS6) is one of the 22 proteins which belong to the <scene name='Ribosomal_protein_S6/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]]. It has a role in regulating translation of RNAs that contain the 5' terminal sequence. It is regulated by ribosomal S6 kinase.
+
-
The images at the left and at the right correspond to one representative RPS6, ''i.e.'' the crystal structure of Ribosomal protein S6 from ''Thermus thermophilus'' ([[2zm6]], chain F).
+
-
 
+
-
{{TOC limit|limit=2}}
+
-
<br />
+
-
<br />
+
-
<br />
+
-
 
+
== 3D Structures of Ribosomal protein S6 ==
== 3D Structures of Ribosomal protein S6 ==
 +
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
===RPS6===
+
*Ribosomal protein S6
-
 
+
-
[[2kjv]] – TtRPS6 – NMR - ''Thermus thermophilus''<br />
+
-
[[2kjw]] – TtRPS6 (mutant)– NMR<br />
+
-
[[2bvz]], [[1ris]] – TtRPS6<br />
+
-
[[2bxj]], [[1cqm]], [[1cqn]], [[1qjh]], [[1lou]] - TtRPS6 (mutant)<br />
+
-
[[2j5a]] – RPS6 – ''Aquifex aeolicus''<br />
+
-
[[1vmb]] – RPS6 – ''Thermotoga maritima''
+
-
 
+
-
===S5 in small ribosomal subunit===
+
-
 
+
-
[[2zm6]], [[1n36]], [[1j5e]], [[3oge]], [[3ogy]], [[3ohc]], [[3ohd]], [[3ohy]], [[3oi0]], [[3oi2]], [[3oi4]], [[3oto]] - TtRPS6 in 30S ribosomal subunit+THX+16S RRNA<br />
+
-
[[2vqe]], [[2vqf]], [[2uuc]], [[2e5l]], [[2uu9]], [[2uua]], [[2uub]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+RNA fragment<br />
+
-
[[3kc4]] – EcRPS6 in 30S ribosomal subunit - ''Escherichia coli''<br />
+
-
[[3i1m]], [[3i1o]], [[3df1]], [[3df3]], [[2vho]], [[2vhp]], [[2avy]], [[2aw7]], [[1pnx]], [[1oaq]], [[3oar]], [[3ofa]], [[3ofb]], [[2ofo]], [[3ofp]], [[3ofx]], [[3ofy]], [[3or9]], [[3ora]] - EcRPS6 in 30S ribosomal subunit+16S RRNA<br />
+
-
[[1i94]], [[1fka]] - TtRPS6 in 30S ribosomal subunit+16S RRNA<br />
+
-
[[1p87]], [[1p6g]] - EcRPS6 in 30S ribosomal subunit+16S RRNA – Cryo-EM<br />
+
-
[[3bbn]] - RPS6 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach
+
-
 
+
-
===S6 in small + large ribosomal subunit===
+
-
 
+
-
[[1ml5]] - EcRPS6 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM
+
-
 
+
-
===S6 in small ribosomal subunit+ chain release factor===
+
-
 
+
-
[[3mr8]], [[3ms0]] – TtRPS6 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA<br />
+
-
[[3d5a]], [[3d5c]] - TtRPS6 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
+
-
[[2b64]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1<br />
+
-
[[2b9m]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2<br />
+
-
[[2x9r]], [[2x9t]], [[2wh1]], [[2wh3]] - TtRPS6 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA<br />
+
-
[[3f1e]], [[3f1g]] - TtRPS6 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit+tRNA+mRNA===
+
-
 
+
-
[[2hgi]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet<br />
+
-
[[2hgp]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
+
-
[[2i2p]], [[2i2u]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
+
-
[[2hgr]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA<br />
+
-
[[1yl4]] – TtRPS6 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator<br />
+
-
[[1pns]] - EcRPS6 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA <br />
+
-
[[1xnq]], [[1xnr]] - TtRPS6 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit+A-site tRNA===
+
-
 
+
-
[[2uxd]] , [[2uxc]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA<br />
+
-
[[1n32]], [[1n33]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA<br />
+
-
[[1n34]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA<br />
+
-
[[1xmo]], [[1xmq]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA<br />
+
-
[[2uxb]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit+P-site tRNA===
+
-
 
+
-
[[3i8g]] - TtRPS6 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA<br />
+
-
[[3i8h]], [[3i9b]], [[3i9d]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA<br />
+
-
[[1ibk]] - TtRPS6 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA<br />
+
-
[[2wwl]] - EcRPS6 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - ''Escherichia coli''<br />
+
-
[[3i1q]] - EcRPS6 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA <br />
+
-
[[3i1s]], [[3i1z]], [[3i21]] - EcRPS6 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA
+
-
 
+
-
===S6 in small ribosomal subunit+A-site tRNA+P-site tRNA===
+
-
+
-
[[1ibl]], [[1ibm]] - TtRPS6 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit+P-site tRNA+E-site tRNA===
+
-
 
+
-
[[2ow8]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA<br />
+
-
[[2b9o]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA<br />
+
-
[[2qnh]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
+
-
[[2wdg]], [[2wdh]], [[2wdk]], [[2wdm]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe
+
-
 
+
-
===S6 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA===
+
-
 
+
-
[[2gy9]], [[2gyb]] - EcRPS6 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM<br />
+
-
[[1jgo]], [[1jgp]], [[1jgq]], [[1gix]] - TtRPS6 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA<br />
+
-
[[3e1a]], [[3e1c]] - EcRPS6 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit + antibiotics===
+
-
 
+
-
[[1i95]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+edeine<br />
+
-
[[1i97]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+tetracycline<br />
+
-
[[3knn]] – TtRPS6 in 30S ribosomal subunit+16S RRNA+capreomycin<br />
+
-
[[1hnw]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline<br />
+
-
[[1hnx]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin <br />
+
-
[[1hnz]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B<br />
+
-
[[1fjg]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin<br />
+
-
[[2qbb]], [[2qb9]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+kasugamyin<br />
+
-
[[2hhh]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+kasugamyin<br />
+
-
[[2f4v]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+designed antibiotic<br />
+
-
[[1vs5]], [[1vs7]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+gentamicin<br />
+
-
[[2qan]], [[2qal]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+neomycin<br />
+
-
[[2qou]], [[2qow]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+spectinomycin<br />
+
-
[[2qoy]], [[2qp0]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin<br />
+
-
[[2z4k]], [[2z4m]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+paromomycin<br />
+
-
[[2j00]], [[2j02]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA<br />
+
-
[[3knj]], [[3knh]] - TtRPS6 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin<br />
+
-
[[3knl]], [[3knm]] - TtRPS6 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin
+
-
 
+
-
===S6 in small ribosomal subunit + ribosome recycling factor===
+
-
 
+
-
[[2qbd]], [[2qbf]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor<br />
+
-
[[2qbh]], [[2qbj]] - EcRPS6 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin<br />
+
-
[[2v46]], [[2v48]] - TtRPS6 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet
+
-
 
+
-
 
+
-
===S6 in small ribosomal subunit + elongation factor===
+
-
 
+
-
[[2wri]], [[2wrk]], [[2xsy]], [[2xuy]] - TtRPS6 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G<br />
+
-
[[2wrn]], [[2wrq]] - TtRPS6 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4<br />
+
-
[[3fic]] - TtRPS6 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A<br />
+
-
[[3fih]] - EcRPS6 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU<br />
+
-
[[3huw]], [[3huy]] - TtRPS6 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P<br />
+
-
[[2xqd]] – TtRPS6 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B<br />
+
-
 
+
-
===S6 in small ribosomal subunit + translation initiation factor===
+
-
 
+
-
[[1i96]] - TtRPS6 in 30S ribosomal subunit+THX+IF3+16S RRNA<br />
+
-
[[1hr0]] - TtRPS6 in 30S ribosomal subunit+THX+IF+16S RRNA
+
-
 
+
-
===S6 in small ribosomal subunit + various proteins===
+
-
 
+
-
[[3kiq]], [[3kis]], [[3kiu]], [[3kix]] - TtRPS6 in 30S ribosomal subunit+toxin RelE+16S RRNA<br />
+
-
[[1voq]], [[1vos]] , [[1vov]], [[1vox]], [[1voz]] - EcRPS6 in 30S ribosomal subunit+protein Y+16S RRNA<br />
+
-
[[3iy8]] – EcRPS6+EcRPS5+EcRPS8+EcRPS9+EcRPS11+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+Leishmania taretolae small subunit<br />
+
-
[[2xfz]], [[2xg1]] – TtRPS6 in 30S ribosomal subunit+colicin E3+E-site tRNA+mRNA+16S RRNA<br />
+
-
===S6 in part of small ribosomal subunit===
+
**[[2kjv]] – TtRPS6 – NMR - ''Thermus thermophilus''<br />
 +
**[[2kjw]] – TtRPS6 (mutant) – NMR<br />
 +
**[[2bvz]], [[1ris]], [[3zzp]] – TtRPS6<br />
 +
**[[2bxj]], [[1cqm]], [[1cqn]], [[1qjh]], [[1lou]] - TtRPS6 (mutant)<br />
 +
[[6i6w]], [[6i6y]], [[7b8v]] – TtRPS6 circular permutation<br />
 +
[[6i69]], [[6i6e]], [[6i6i]], [[6i6o]], [[6i6s]], [[6i6u]] – TtRPS6 (mutant) circular permutation<br />
 +
**[[2j5a]] – RPS6 – ''Aquifex aeolicus''<br />
 +
**[[1vmb]] – RPS6 – ''Thermotoga maritima''<br />
 +
**[[3r3t]] – RPS6 – ''Bacillus anthracis''
-
[[1qd7]] – TtRPS6+TtRPS4+TtRPS5+TtRPS7+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
+
*Ribosomal protein S6 in part of small ribosomal subunit
-
[[1g1x]] - TtRPS6+TtRPS15+TtRPS18+16S RRNA fragment
+
 +
**[[1qd7]] – TtRPS6+TtRPS4+TtRPS5+TtRPS7+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
 +
**[[1g1x]] - TtRPS6+TtRPS15+TtRPS18+16S RRNA fragment<br />
 +
**[[3j16]] – yRPS6 + yRPS24 + yRPS30 + yRPL6 + yRPL10 + yRPL11 + 18S RRNA + 28SRRNA + P-site tRNA – yeast - Cryo EM
 +
}}
 +
== References ==
 +
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein S6 (PDB code 2bvz)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein S6

Updated on 01-March-2022

6i6w, 6i6y, 7b8v – TtRPS6 circular permutation
6i69, 6i6e, 6i6i, 6i6o, 6i6s, 6i6u – TtRPS6 (mutant) circular permutation

References

  1. ↑ Ruvinsky I, Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem Sci. 2006 Jun;31(6):342-8. Epub 2006 May 6. PMID:16679021 doi:http://dx.doi.org/10.1016/j.tibs.2006.04.003

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Ribosomal_protein_S6"
Personal tools