3mxa

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[[Image:3mxa.png|left|200px]]
 
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==Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus==
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The line below this paragraph, containing "STRUCTURE_3mxa", creates the "Structure Box" on the page.
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<StructureSection load='3mxa' size='340' side='right'caption='[[3mxa]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3mxa]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MXA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_3mxa| PDB=3mxa | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mxa OCA], [https://pdbe.org/3mxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mxa RCSB], [https://www.ebi.ac.uk/pdbsum/3mxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mxa ProSAT]</span></td></tr>
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</table>
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===Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus===
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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The line below this paragraph, {{ABSTRACT_PUBMED_20846960}}, adds the Publication Abstract to the page
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/3mxa_consurf.spt"</scriptWhenChecked>
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(as it appears on PubMed at http://www.pubmed.gov), where 20846960 is the PubMed ID number.
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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{{ABSTRACT_PUBMED_20846960}}
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mxa ConSurf].
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==About this Structure==
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<div style="clear:both"></div>
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[[3mxa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXA OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:20846960</ref><references group="xtra"/>
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[[Category: Chlamydomonas reinhardtii]]
[[Category: Chlamydomonas reinhardtii]]
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[[Category: Coloma, J.]]
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[[Category: Large Structures]]
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[[Category: Montoya, G.]]
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[[Category: Coloma J]]
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[[Category: Munoz, I G.]]
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[[Category: Montoya G]]
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[[Category: Prieto, J.]]
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[[Category: Munoz IG]]
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[[Category: Subramanian, S.]]
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[[Category: Prieto J]]
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[[Category: Subramanian S]]

Current revision

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

PDB ID 3mxa

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OCA

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