3m9b

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[[Image:3m9b.png|left|200px]]
 
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==Crystal structure of the amino terminal coiled coil domain and the inter domain of the Mycobacterium tuberculosis proteasomal ATPase Mpa==
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The line below this paragraph, containing "STRUCTURE_3m9b", creates the "Structure Box" on the page.
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<StructureSection load='3m9b' size='340' side='right'caption='[[3m9b]], [[Resolution|resolution]] 3.94&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3m9b]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M9B FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.94&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m9b OCA], [https://pdbe.org/3m9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m9b RCSB], [https://www.ebi.ac.uk/pdbsum/3m9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m9b ProSAT]</span></td></tr>
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{{STRUCTURE_3m9b| PDB=3m9b | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARC_MYCTU ARC_MYCTU] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Is required but not sufficient to confer resistance against the lethal effects of reactive nitrogen intermediates (RNI), antimicrobial molecules produced by activated macrophages and other cell types.[HAMAP-Rule:MF_02112]<ref>PMID:14671303</ref> <ref>PMID:15659170</ref> <ref>PMID:17082771</ref> <ref>PMID:19836337</ref> <ref>PMID:20203624</ref>
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===Crystal structure of the amino terminal coiled coil domain and the inter domain of the Mycobacterium tuberculosis proteasomal ATPase Mpa===
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==See Also==
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*[[ATPase 3D structures|ATPase 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 20953180 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_20953180}}
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==About this Structure==
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[[3m9b]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9B OCA].
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==Reference==
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<ref group="xtra">PMID:20953180</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Li, H.]]
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[[Category: Li H]]
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[[Category: Wang, T.]]
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[[Category: Wang T]]

Current revision

Crystal structure of the amino terminal coiled coil domain and the inter domain of the Mycobacterium tuberculosis proteasomal ATPase Mpa

PDB ID 3m9b

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