3q0n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE== | |
| - | + | <StructureSection load='3q0n' size='340' side='right'caption='[[3q0n]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3q0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0n OCA], [https://pdbe.org/3q0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0n RCSB], [https://www.ebi.ac.uk/pdbsum/3q0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0n ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hall TMT]] | ||
| + | [[Category: Lu G]] | ||
Current revision
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE
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