2l81

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[[Image:2l81.jpg|left|200px]]
 
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==Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A==
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The line below this paragraph, containing "STRUCTURE_2l81", creates the "Structure Box" on the page.
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<StructureSection load='2l81' size='340' side='right'caption='[[2l81]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2l81]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L81 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L81 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l81 OCA], [https://pdbe.org/2l81 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l81 RCSB], [https://www.ebi.ac.uk/pdbsum/2l81 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l81 ProSAT]</span></td></tr>
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{{STRUCTURE_2l81| PDB=2l81 | SCENE= }}
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</table>
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== Function ==
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===Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A===
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[https://www.uniprot.org/uniprot/CASL_HUMAN CASL_HUMAN] Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
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__TOC__
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</StructureSection>
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==About this Structure==
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[[2l81]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L81 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Ciccosanti, C T.]]
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[[Category: Acton TB]]
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[[Category: Everett, J T.]]
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[[Category: Ciccosanti CT]]
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[[Category: Huang, Y J.]]
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[[Category: Everett JT]]
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[[Category: Liu, G.]]
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[[Category: Huang YJ]]
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[[Category: Montelione, G T.]]
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[[Category: Liu G]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Patel, D.]]
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[[Category: Patel D]]
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[[Category: Tong, S.]]
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[[Category: Tong S]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]

Current revision

Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A

PDB ID 2l81

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