3p68

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[[Image:3p68.jpg|left|200px]]
 
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==Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme==
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The line below this paragraph, containing "STRUCTURE_3p68", creates the "Structure Box" on the page.
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<StructureSection load='3p68' size='340' side='right'caption='[[3p68]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P68 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU3:GOLD+3++ION'>AU3</scene></td></tr>
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{{STRUCTURE_3p68| PDB=3p68 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p68 OCA], [https://pdbe.org/3p68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p68 RCSB], [https://www.ebi.ac.uk/pdbsum/3p68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p68 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Gold nanoparticles are useful in biomedical applications due to their distinct optical properties and high chemical stability. Reports of the biogenic formation of gold colloids from gold complexes has also led to an increased level of interest in the biomineralization of gold. However, the mechanism responsible for biomolecule-directed gold nanoparticle formation remains unclear due to the lack of structural information about biological systems and the fast kinetics of biomimetic chemical systems in solution. Here we show that intact single crystals of lysozyme can be used to study the time-dependent, protein-directed growth of gold nanoparticles. The protein crystals slow down the growth of the gold nanoparticles, allowing detailed kinetic studies to be carried out, and permit a three-dimensional structural characterization that would be difficult to achieve in solution. Furthermore, we show that additional chemical species can be used to fine-tune the growth rate of the gold nanoparticles.
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===Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme===
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Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.,Wei H, Wang Z, Zhang J, House S, Gao YG, Yang L, Robinson H, Tan LH, Xing H, Hou C, Robertson IM, Zuo JM, Lu Y Nat Nanotechnol. 2011 Feb;6(2):93-7. Epub 2011 Jan 30. PMID:21278750<ref>PMID:21278750</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3p68" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[3p68]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P68 OCA].
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Gao, Y G.]]
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[[Category: Gao Y-G]]
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[[Category: Hou, C.]]
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[[Category: Hou C]]
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[[Category: House, S.]]
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[[Category: House S]]
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[[Category: Lu, Y.]]
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[[Category: Lu Y]]
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[[Category: Robertson, I M.]]
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[[Category: Robertson IM]]
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[[Category: Robinson, H.]]
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[[Category: Robinson H]]
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[[Category: Tan, L H.]]
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[[Category: Tan LH]]
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[[Category: Wang, Z.]]
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[[Category: Wang Z]]
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[[Category: Wei, H.]]
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[[Category: Wei H]]
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[[Category: Xing, H.]]
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[[Category: Xing H]]
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[[Category: Yang, L.]]
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[[Category: Yang L]]
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[[Category: Zhang, J.]]
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[[Category: Zhang J]]
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[[Category: Zuo, J M.]]
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[[Category: Zuo J-M]]

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Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme

PDB ID 3p68

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