2i8a

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[[Image:2i8a.jpg|left|200px]]<br /><applet load="2i8a" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2i8a, resolution 1.64&Aring;" />
 
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'''Salmonella typhimurium liganded by phosphate ion at 1.64A resolution'''<br />
 
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==About this Structure==
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==Salmonella typhimurium liganded by phosphate ion at 1.64A resolution==
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2I8A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8A OCA].
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<StructureSection load='2i8a' size='340' side='right'caption='[[2i8a]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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[[Category: Salmonella typhimurium]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2i8a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I8A FirstGlance]. <br>
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[[Category: Uridine phosphorylase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
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[[Category: Gabdoulkhakov, A.G.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Mikhailov, A.M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i8a OCA], [https://pdbe.org/2i8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i8a RCSB], [https://www.ebi.ac.uk/pdbsum/2i8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i8a ProSAT]</span></td></tr>
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[[Category: Timofeev, V.I.]]
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</table>
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[[Category: PO4]]
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== Function ==
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[[Category: nucleoside phosphorylase]]
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[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
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[[Category: transferase]]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/2i8a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i8a ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:45:40 2008''
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==See Also==
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*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Gabdoulkhakov AG]]
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[[Category: Mikhailov AM]]
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[[Category: Timofeev VI]]

Current revision

Salmonella typhimurium liganded by phosphate ion at 1.64A resolution

PDB ID 2i8a

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