2dfs

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[[Image:2dfs.png|left|200px]]
 
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==3-D structure of Myosin-V inhibited state==
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The line below this paragraph, containing "STRUCTURE_2dfs", creates the "Structure Box" on the page.
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<StructureSection load='2dfs' size='340' side='right'caption='[[2dfs]], [[Resolution|resolution]] 24.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dfs]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 24&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfs OCA], [https://pdbe.org/2dfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfs RCSB], [https://www.ebi.ac.uk/pdbsum/2dfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfs ProSAT]</span></td></tr>
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{{STRUCTURE_2dfs| PDB=2dfs | SCENE= }}
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</table>
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== Function ==
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===3-D structure of Myosin-V inhibited state===
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[https://www.uniprot.org/uniprot/MYO5A_CHICK MYO5A_CHICK] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16625208}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16625208 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16625208}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dfs ConSurf].
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[[2dfs]] is a 14 chain structure of [[Calmodulin]] and [[Myosin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFS OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Calmodulin]]
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*[[Calmodulin 3D structures|Calmodulin 3D structures]]
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*[[Myosin]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:16625208</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Krementsova, E B.]]
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[[Category: Krementsova EB]]
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[[Category: Liu, J.]]
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[[Category: Liu J]]
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[[Category: Taylor, D W.]]
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[[Category: Taylor DW]]
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[[Category: Taylor, K A.]]
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[[Category: Taylor KA]]
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[[Category: Trybus, K M.]]
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[[Category: Trybus KM]]

Current revision

3-D structure of Myosin-V inhibited state

PDB ID 2dfs

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