3q1r
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a bacterial RNase P holoenzyme in complex with TRNA and in the presence of 5' leader== | |
| + | <StructureSection load='3q1r' size='340' side='right'caption='[[3q1r]], [[Resolution|resolution]] 4.21Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3q1r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3okb 3okb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q1R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q1R FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.21Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q1r OCA], [https://pdbe.org/3q1r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q1r RCSB], [https://www.ebi.ac.uk/pdbsum/3q1r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q1r ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNPA_THEMA RNPA_THEMA] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | |
| - | + | *[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermotoga maritima]] | ||
| + | [[Category: Mondragon A]] | ||
| + | [[Category: Ostermanm A]] | ||
| + | [[Category: Pan T]] | ||
| + | [[Category: Reiter NJ]] | ||
| + | [[Category: Swinger KK]] | ||
| + | [[Category: Torres-Larios A]] | ||
Current revision
Crystal structure of a bacterial RNase P holoenzyme in complex with TRNA and in the presence of 5' leader
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