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3qr6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure Analysis of H185F Mutant of Human CLIC1== | |
| + | <StructureSection load='3qr6' size='340' side='right'caption='[[3qr6]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3qr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QR6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr6 OCA], [https://pdbe.org/3qr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qr6 RCSB], [https://www.ebi.ac.uk/pdbsum/3qr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qr6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Achilonu IA]] | ||
| + | [[Category: Dirr HW]] | ||
| + | [[Category: Fanucchi S]] | ||
| + | [[Category: Fernandes MA]] | ||
Current revision
Crystal Structure Analysis of H185F Mutant of Human CLIC1
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