This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lox
From Proteopedia
(Difference between revisions)
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3lox.jpg|left|200px]] | ||
| - | + | ==HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound== | |
| - | + | <StructureSection load='3lox' size='340' side='right'caption='[[3lox]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3lox]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MCX:(1R,2S,5S)-N-[(2S,3R)-4-AMINO-1-CYCLOBUTYL-3-HYDROXY-4-OXOBUTAN-2-YL]-6,6-DIMETHYL-3-{3-METHYL-N-[(1-METHYLCYCLOHEXYL)CARBAMOYL]-L-VALYL}-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE'>MCX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lox OCA], [https://pdbe.org/3lox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lox RCSB], [https://www.ebi.ac.uk/pdbsum/3lox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lox ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9ELS8_9HEPC Q9ELS8_9HEPC] | ||
| - | == | + | ==See Also== |
| - | + | *[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]] | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Hepatitis C virus genotype 1a]] | |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Prongay AJ]] | |
| - | + | ||
| - | + | ||
| - | [[ | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: Hepatitis | + | |
| - | [[Category: Prongay | + | |
Current revision
HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound
| |||||||||||
