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2b6b

From Proteopedia

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[[Image:2b6b.png|left|200px]]
 
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==Cryo EM structure of Dengue complexed with CRD of DC-SIGN==
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The line below this paragraph, containing "STRUCTURE_2b6b", creates the "Structure Box" on the page.
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<SX load='2b6b' size='340' side='right' viewer='molstar' caption='[[2b6b]], [[Resolution|resolution]] 25.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2b6b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6b OCA], [https://pdbe.org/2b6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6b RCSB], [https://www.ebi.ac.uk/pdbsum/2b6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6b ProSAT]</span></td></tr>
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{{STRUCTURE_2b6b| PDB=2b6b | SCENE= }}
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</table>
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== Function ==
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===Cryo EM structure of Dengue complexed with CRD of DC-SIGN===
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[https://www.uniprot.org/uniprot/Q9WDA7_9FLAV Q9WDA7_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16469696}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16469696 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16469696}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6b ConSurf].
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[[2b6b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6B OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</SX>
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<ref group="xtra">PMID:16469696</ref><references group="xtra"/>
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[[Category: Dengue virus]]
[[Category: Dengue virus]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bator-Kelly, C M.]]
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[[Category: Large Structures]]
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[[Category: Battisti, A J.]]
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[[Category: Bator-Kelly CM]]
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[[Category: Chipman, P R.]]
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[[Category: Battisti AJ]]
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[[Category: Gregorio, G.]]
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[[Category: Chipman PR]]
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[[Category: Hendrickson, W A.]]
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[[Category: Gregorio G]]
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[[Category: Kuhn, R J.]]
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[[Category: Hendrickson WA]]
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[[Category: Pokidysheva, E.]]
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[[Category: Kuhn RJ]]
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[[Category: Rossmann, M G.]]
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[[Category: Pokidysheva E]]
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[[Category: Zhang, Y.]]
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[[Category: Rossmann MG]]
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[[Category: Zhang Y]]

Current revision

Cryo EM structure of Dengue complexed with CRD of DC-SIGN

2b6b, resolution 25.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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