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3laf

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[[Image:3laf.jpg|left|200px]]
 
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==Structure of DCC, a netrin-1 receptor==
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The line below this paragraph, containing "STRUCTURE_3laf", creates the "Structure Box" on the page.
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<StructureSection load='3laf' size='340' side='right'caption='[[3laf]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3laf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LAF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3laf| PDB=3laf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3laf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3laf OCA], [https://pdbe.org/3laf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3laf RCSB], [https://www.ebi.ac.uk/pdbsum/3laf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3laf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DCC_RAT DCC_RAT] Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene (By similarity).<ref>PMID:8861902</ref>
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===Structure of DCC, a netrin-1 receptor===
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==See Also==
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*[[Netrin receptor|Netrin receptor]]
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== References ==
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==About this Structure==
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<references/>
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[[3laf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAF OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Chen, Q.]]
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[[Category: Chen Q]]
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[[Category: Liu, J H.]]
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[[Category: Liu J-H]]
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[[Category: Wang, J H.]]
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[[Category: Wang J-H]]

Current revision

Structure of DCC, a netrin-1 receptor

PDB ID 3laf

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