3qyb
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain== | |
| - | + | <StructureSection load='3qyb' size='340' side='right'caption='[[3qyb]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3qyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QYB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qyb OCA], [https://pdbe.org/3qyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qyb RCSB], [https://www.ebi.ac.uk/pdbsum/3qyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qyb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBCD4_HUMAN TBCD4_HUMAN] May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.<ref>PMID:15971998</ref> <ref>PMID:18771725</ref> <ref>PMID:22908308</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Park SY]] | ||
| + | [[Category: Shoelson SE]] | ||
Current revision
X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain
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