3pkm

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[[Image:3pkm.jpg|left|200px]]
 
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==Crystal structure of Cas6 with its substrate RNA==
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The line below this paragraph, containing "STRUCTURE_3pkm", creates the "Structure Box" on the page.
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<StructureSection load='3pkm' size='340' side='right'caption='[[3pkm]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pkm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PKM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.103&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pkm OCA], [https://pdbe.org/3pkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pkm RCSB], [https://www.ebi.ac.uk/pdbsum/3pkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pkm ProSAT]</span></td></tr>
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{{STRUCTURE_3pkm| PDB=3pkm | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAS6_PYRFU CAS6_PYRFU] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism. This protein processes pre-crRNA into individual crRNA units, with an 8-nt 5'-repeat DNA tag that may help other proteins recognize the crRNA. Further processing occurs at their 3' termini in this organism. Generates a 5'-hydroxy and 2',3'-cyclic phosphodiester.<ref>PMID:19141480</ref> <ref>PMID:20884784</ref>
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===Crystal structure of Cas6 with its substrate RNA===
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==See Also==
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*[[CRISPR subtype III-B (Cmr complex)|CRISPR subtype III-B (Cmr complex)]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 21300293 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_21300293}}
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[[Category: Large Structures]]
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==About this Structure==
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[[3pkm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PKM OCA].
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==Reference==
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<ref group="xtra">PMID:21300293</ref><references group="xtra"/>
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Li, H.]]
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[[Category: Li H]]
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[[Category: Preamplume, G.]]
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[[Category: Preamplume G]]
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[[Category: Wang, R.]]
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[[Category: Wang R]]

Current revision

Crystal structure of Cas6 with its substrate RNA

PDB ID 3pkm

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OCA

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