3p3w

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[[Image:3p3w.jpg|left|200px]]
 
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==Structure of a dimeric GluA3 N-terminal domain (NTD) at 4.2 A resolution==
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The line below this paragraph, containing "STRUCTURE_3p3w", creates the "Structure Box" on the page.
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<StructureSection load='3p3w' size='340' side='right'caption='[[3p3w]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p3w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3W FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3w OCA], [https://pdbe.org/3p3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3w RCSB], [https://www.ebi.ac.uk/pdbsum/3p3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3w ProSAT]</span></td></tr>
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{{STRUCTURE_3p3w| PDB=3p3w | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GRIA3_RAT GRIA3_RAT] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity).
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===Structure of a dimeric GluA3 N-terminal domain (NTD) at 4.2 A resolution===
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==See Also==
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*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21317871 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21317871}}
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==About this Structure==
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[[3p3w]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3W OCA].
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==Reference==
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<ref group="xtra">PMID:21317871</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Greger, I H.]]
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[[Category: Greger IH]]
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[[Category: Rossmann, M.]]
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[[Category: Rossmann M]]
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[[Category: Sukumaran, M.]]
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[[Category: Sukumaran M]]

Current revision

Structure of a dimeric GluA3 N-terminal domain (NTD) at 4.2 A resolution

PDB ID 3p3w

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