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3pos
From Proteopedia
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| - | [[Image:3pos.jpg|left|200px]] | ||
| - | + | ==Crystal structure of the globular domain of human calreticulin== | |
| - | + | <StructureSection load='3pos' size='340' side='right'caption='[[3pos]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3pos]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3POS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pos OCA], [https://pdbe.org/3pos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pos RCSB], [https://www.ebi.ac.uk/pdbsum/3pos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pos ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/CALR_HUMAN CALR_HUMAN] Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).<ref>PMID:7876246</ref> <ref>PMID:11149926</ref> | |
| - | + | ||
| - | == | + | |
| - | [[3pos]] is a 3 chain structure | + | |
==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[Calreticulin 3D structures|Calreticulin 3D structures]] |
| + | *[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arlaud | + | [[Category: Large Structures]] |
| - | [[Category: Chouquet | + | [[Category: Arlaud GJ]] |
| - | [[Category: Frachet | + | [[Category: Chouquet A]] |
| - | [[Category: Gaboriaud | + | [[Category: Frachet P]] |
| - | [[Category: Houen | + | [[Category: Gaboriaud C]] |
| - | [[Category: Ling | + | [[Category: Houen G]] |
| - | [[Category: Paidassi | + | [[Category: Ling W-L]] |
| + | [[Category: Paidassi H]] | ||
Current revision
Crystal structure of the globular domain of human calreticulin
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Categories: Homo sapiens | Large Structures | Arlaud GJ | Chouquet A | Frachet P | Gaboriaud C | Houen G | Ling W-L | Paidassi H
