3chm

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[[Image:3chm.png|left|200px]]
 
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==Crystal structure of PCI domain from A. thaliana COP9 signalosome subunit 7 (CSN7)==
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The line below this paragraph, containing "STRUCTURE_3chm", creates the "Structure Box" on the page.
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<StructureSection load='3chm' size='340' side='right'caption='[[3chm]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3chm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CHM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3chm| PDB=3chm | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3chm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3chm OCA], [https://pdbe.org/3chm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3chm RCSB], [https://www.ebi.ac.uk/pdbsum/3chm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3chm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSN7_ARATH CSN7_ARATH] Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.<ref>PMID:11337587</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/3chm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3chm ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of PCI domain from A. thaliana COP9 signalosome subunit 7 (CSN7)===
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==See Also==
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*[[Signalosome|Signalosome]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18854373 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_18854373}}
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==About this Structure==
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[[3chm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CHM OCA].
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==Reference==
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<ref group="xtra">PMID:18854373</ref><ref group="xtra">PMID:17077498</ref><references group="xtra"/>
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Dessau, M.]]
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[[Category: Large Structures]]
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[[Category: Hirsch, J A.]]
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[[Category: Dessau M]]
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[[Category: Alternative splicing]]
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[[Category: Hirsch JA]]
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[[Category: Cytoplasm]]
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[[Category: Developmental protein]]
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[[Category: Heat/arm repeat]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Phytochrome signaling pathway]]
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[[Category: Plant protein]]
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[[Category: Signalosome]]
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[[Category: Winged helix motif]]
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Current revision

Crystal structure of PCI domain from A. thaliana COP9 signalosome subunit 7 (CSN7)

PDB ID 3chm

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OCA

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