2y0s

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[[Image:2y0s.png|left|200px]]
 
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==Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group==
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The line below this paragraph, containing "STRUCTURE_2y0s", creates the "Structure Box" on the page.
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<StructureSection load='2y0s' size='340' side='right'caption='[[2y0s]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2y0s]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_shibatae Saccharolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0S FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2y0s| PDB=2y0s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0s OCA], [https://pdbe.org/2y0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0s RCSB], [https://www.ebi.ac.uk/pdbsum/2y0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0s ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPO1C_SACSH RPO1C_SACSH] DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.[HAMAP-Rule:MF_00411]<ref>PMID:19419240</ref> <ref>PMID:21265742</ref> <ref>PMID:22848102</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We review recent results on the complete structure of the archaeal RNAP (RNA polymerase) enzyme of Sulfolobus shibatae. We compare the three crystal forms in which this RNAP packs (space groups P212121, P21212 and P21) and provide a preliminary biophysical characterization of the newly identified 13-subunit Rpo13. The availability of different crystal forms for this RNAP allows the analysis of the packing degeneracy and the intermolecular interactions that determine this degeneracy. We observe the pivotal role played by the protruding stalk composed of subunits Rpo4 and Rpo7 in the lattice contacts. Aided by MALLS (multi-angle laser light scattering), we have initiated the biophysical characterization of the recombinantly expressed and purified subunit Rpo13, a necessary step towards the understanding of Rpo13's role in archaeal transcription.
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===CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE RNA POLYMERASE IN P21 SPACE GROUP===
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Archaeal RNA polymerase: the influence of the protruding stalk in crystal packing and preliminary biophysical analysis of the Rpo13 subunit.,Wojtas M, Peralta B, Ondiviela M, Mogni M, Bell SD, Abrescia NG Biochem Soc Trans. 2011 Jan 19;39(1):25-30. PMID:21265742<ref>PMID:21265742</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2y0s" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_21265742}}, adds the Publication Abstract to the page
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21265742 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21265742}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[2y0s]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_shibatae Sulfolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0S OCA].
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[[Category: Saccharolobus shibatae]]
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[[Category: Abrescia NGA]]
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==Reference==
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[[Category: Bell SD]]
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<ref group="xtra">PMID:21265742</ref><ref group="xtra">PMID:19419240</ref><references group="xtra"/>
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[[Category: Mogni M]]
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Ondiviela M]]
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[[Category: Sulfolobus shibatae]]
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[[Category: Peralta B]]
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[[Category: Abrescia, N G.A.]]
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[[Category: Wojtas M]]
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[[Category: Bell, S D.]]
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[[Category: Mogni, M.]]
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[[Category: Ondiviela, M.]]
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[[Category: Peralta, B.]]
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[[Category: Wojtas, M.]]
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Current revision

Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group

PDB ID 2y0s

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