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1ohy

From Proteopedia

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[[Image:1ohy.png|left|200px]]
 
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==4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-ethynyl GABA==
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The line below this paragraph, containing "STRUCTURE_1ohy", creates the "Structure Box" on the page.
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<StructureSection load='1ohy' size='340' side='right'caption='[[1ohy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ohy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OHY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GEG:(4E)-4-AMINOHEX-4-ENOIC+ACID'>GEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_1ohy| PDB=1ohy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ohy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ohy OCA], [https://pdbe.org/1ohy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ohy RCSB], [https://www.ebi.ac.uk/pdbsum/1ohy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ohy ProSAT]</span></td></tr>
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</table>
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===4-AMINOBUTYRATE-AMINOTRANSFERASE INACTIVATED BY GAMMA-ETHYNYL GABA===
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== Function ==
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[https://www.uniprot.org/uniprot/GABT_PIG GABT_PIG] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_14534310}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14534310 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oh/1ohy_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14534310}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1ohy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OHY OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ohy ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:14534310</ref><ref group="xtra">PMID:10393538</ref><references group="xtra"/>
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</StructureSection>
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[[Category: 4-aminobutyrate transaminase]]
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Schirmer, T.]]
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[[Category: Schirmer T]]
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[[Category: Storici, P.]]
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[[Category: Storici P]]
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[[Category: 4-aminobutyric acid]]
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[[Category: Aminotransferase]]
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[[Category: Antiepileptic drug target]]
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[[Category: Mitochondrion]]
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[[Category: Neurotransmitter degradation]]
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[[Category: Plp-dependent enzyme]]
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[[Category: Transferase]]
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[[Category: Transit peptide]]
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[[Category: Vigabatrin pyridoxal phosphate]]
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Current revision

4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-ethynyl GABA

PDB ID 1ohy

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