This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1tmm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1tmm" [edit=sysop:move=sysop])
Current revision (13:30, 13 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1tmm.png|left|200px]]
 
-
<!--
+
==Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin==
-
The line below this paragraph, containing "STRUCTURE_1tmm", creates the "Structure Box" on the page.
+
<StructureSection load='1tmm' size='340' side='right'caption='[[1tmm]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1tmm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TMM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HHR:6-HYDROXYMETHYLPTERIN'>HHR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_1tmm| PDB=1tmm | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tmm OCA], [https://pdbe.org/1tmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tmm RCSB], [https://www.ebi.ac.uk/pdbsum/1tmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tmm ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/1tmm_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tmm ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin===
+
==See Also==
-
 
+
*[[HPPK 3D structures|HPPK 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15952765}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 15952765 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15952765}}
+
-
 
+
-
==About this Structure==
+
-
[[1tmm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMM OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:15952765</ref><ref group="xtra">PMID:10378268</ref><ref group="xtra">PMID:11080626</ref><ref group="xtra">PMID:11311059</ref><references group="xtra"/>
+
-
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Blaszczyk, J.]]
+
[[Category: Large Structures]]
-
[[Category: Ji, X.]]
+
[[Category: Blaszczyk J]]
-
[[Category: Li, Y.]]
+
[[Category: Ji X]]
-
[[Category: Shi, G.]]
+
[[Category: Li Y]]
-
[[Category: Wu, Y.]]
+
[[Category: Shi G]]
-
[[Category: Yan, H.]]
+
[[Category: Wu Y]]
-
[[Category: 6-hydroxymethyl-7]]
+
[[Category: Yan H]]
-
[[Category: 6-hydroxymethylpterin]]
+
-
[[Category: 8-dihydropterin]]
+
-
[[Category: Antimicrobial agent]]
+
-
[[Category: Catalytic mechanism]]
+
-
[[Category: Drug design]]
+
-
[[Category: Folate]]
+
-
[[Category: Hppk]]
+
-
[[Category: Product release]]
+
-
[[Category: Pterin]]
+
-
[[Category: Pyrophosphokinase]]
+
-
[[Category: Pyrophosphoryl transfer]]
+
-
[[Category: Substrate specificity]]
+
-
[[Category: Ternary complex]]
+
-
[[Category: Transferase]]
+
-
[[Category: X-ray crystallography]]
+

Current revision

Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin

PDB ID 1tmm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tmm"
Personal tools