2fsf

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[[Image:2fsf.png|left|200px]]
 
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==Escherichia coli SecA, the preprotein translocase dimeric ATPase==
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The line below this paragraph, containing "STRUCTURE_2fsf", creates the "Structure Box" on the page.
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<StructureSection load='2fsf' size='340' side='right'caption='[[2fsf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fsf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FSF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fsf OCA], [https://pdbe.org/2fsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fsf RCSB], [https://www.ebi.ac.uk/pdbsum/2fsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fsf ProSAT]</span></td></tr>
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{{STRUCTURE_2fsf| PDB=2fsf | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SECA_ECOLI SECA_ECOLI] Required for protein export, interacts with the SecYEG preprotein conducting channel. SecA has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.<ref>PMID:15140892</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/2fsf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fsf ConSurf].
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<div style="clear:both"></div>
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===Escherichia coli SecA, the preprotein translocase dimeric ATPase===
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==See Also==
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*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
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*[[SecA|SecA]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_17229438}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 17229438 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_17229438}}
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==About this Structure==
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[[2fsf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSF OCA].
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==Reference==
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<ref group="xtra">PMID:17229438</ref><ref group="xtra">PMID:15710424</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Economou, A.]]
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[[Category: Large Structures]]
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[[Category: Papanikolau, Y.]]
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[[Category: Economou A]]
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[[Category: Petratos, K.]]
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[[Category: Papanikolau Y]]
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[[Category: Atpase]]
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[[Category: Petratos K]]
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[[Category: Dna-rna helicase]]
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[[Category: Protein translocation]]
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[[Category: Protein transport]]
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[[Category: Seca]]
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Current revision

Escherichia coli SecA, the preprotein translocase dimeric ATPase

PDB ID 2fsf

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