3h5e

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[[Image:3h5e.png|left|200px]]
 
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==LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_3h5e", creates the "Structure Box" on the page.
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<StructureSection load='3h5e' size='340' side='right'caption='[[3h5e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3h5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H5E FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h5e OCA], [https://pdbe.org/3h5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h5e RCSB], [https://www.ebi.ac.uk/pdbsum/3h5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h5e ProSAT]</span></td></tr>
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{{STRUCTURE_3h5e| PDB=3h5e | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEUD_MYCTU LEUD_MYCTU] Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h5/3h5e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h5e ConSurf].
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<div style="clear:both"></div>
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===LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis===
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==See Also==
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*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
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*[[Isopropylmalate isomerase|Isopropylmalate isomerase]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_20938981}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 20938981 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_20938981}}
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==About this Structure==
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[[3h5e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5E OCA].
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==Reference==
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<ref group="xtra">PMID:20938981</ref><ref group="xtra">PMID:19194004</ref><references group="xtra"/>
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[[Category: 3-isopropylmalate dehydratase]]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Geerlof, A.]]
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[[Category: Geerlof A]]
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[[Category: Manikandan, K.]]
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[[Category: Manikandan K]]
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[[Category: Weiss, M S.]]
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[[Category: Weiss MS]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Branched-chain amino acid biosynthesis]]
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[[Category: Isopropylmalate isomerase]]
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[[Category: Leucine biosynthesis]]
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[[Category: Leud]]
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[[Category: Lyase]]
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[[Category: M tuberculosis]]
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Current revision

LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis

PDB ID 3h5e

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