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2jrf
From Proteopedia
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| - | [[Image:2jrf.jpg|left|200px]]<br /><applet load="2jrf" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2jrf" /> | ||
| - | '''Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.'''<br /> | ||
| - | == | + | ==Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.== |
| - | + | <StructureSection load='2jrf' size='340' side='right'caption='[[2jrf]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2jrf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JRF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrf OCA], [https://pdbe.org/2jrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jrf RCSB], [https://www.ebi.ac.uk/pdbsum/2jrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jrf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TPPP3_HUMAN TPPP3_HUMAN] Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis.<ref>PMID:17105200</ref> <ref>PMID:19633818</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/2jrf_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jrf ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Acton | + | [[Category: Acton TB]] |
| - | [[Category: Aramini | + | [[Category: Aramini JM]] |
| - | [[Category: Baran | + | [[Category: Baran MC]] |
| - | [[Category: Cunningham | + | [[Category: Cunningham K]] |
| - | [[Category: Liu | + | [[Category: Liu J]] |
| - | [[Category: Montelione | + | [[Category: Montelione GT]] |
| - | + | [[Category: Nwosu C]] | |
| - | [[Category: Nwosu | + | [[Category: Rajan PK]] |
| - | [[Category: Rajan | + | [[Category: Rossi P]] |
| - | [[Category: Rossi | + | [[Category: Rost B]] |
| - | [[Category: Rost | + | [[Category: Shastry R]] |
| - | [[Category: Shastry | + | [[Category: Xiao R]] |
| - | [[Category: Xiao | + | |
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Current revision
Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.
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Categories: Homo sapiens | Large Structures | Acton TB | Aramini JM | Baran MC | Cunningham K | Liu J | Montelione GT | Nwosu C | Rajan PK | Rossi P | Rost B | Shastry R | Xiao R
