3d4x

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[[Image:3d4x.png|left|200px]]
 
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==Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.2 angstrom resolution==
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The line below this paragraph, containing "STRUCTURE_3d4x", creates the "Structure Box" on the page.
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<StructureSection load='3d4x' size='340' side='right'caption='[[3d4x]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d4x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Felis_catus Felis catus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_3d4x| PDB=3d4x | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4x OCA], [https://pdbe.org/3d4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4x RCSB], [https://www.ebi.ac.uk/pdbsum/3d4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4x ProSAT]</span></td></tr>
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</table>
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===Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.2 angstrom resolution===
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== Function ==
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[https://www.uniprot.org/uniprot/HBB_FELCA HBB_FELCA] Involved in oxygen transport from the lung to the various peripheral tissues.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17909297 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d4x_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17909297}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3d4x]] is a 4 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Felis_catus Felis catus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4X OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d4x ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hemoglobin]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:17909297</ref><ref group="xtra">PMID:19255493</ref><ref group="xtra">PMID:19200047</ref><references group="xtra"/>
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[[Category: Felis catus]]
[[Category: Felis catus]]
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[[Category: Balasubramanian, M.]]
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[[Category: Large Structures]]
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[[Category: Moorthy, Pon Sathya.]]
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[[Category: Balasubramanian M]]
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[[Category: Neelagandan, K.]]
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[[Category: Neelagandan K]]
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[[Category: Ponnuswamy, M N.]]
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[[Category: Ponnuswamy MN]]
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[[Category: Allosteric mechanism]]
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[[Category: Sathya Moorthy P]]
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[[Category: Felis silvestris catus]]
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[[Category: Heme]]
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[[Category: Hemoglobin]]
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[[Category: Iron]]
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[[Category: Low oxygen affinity]]
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[[Category: Monoclinic]]
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[[Category: Oxygen storage]]
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[[Category: Oxygen transport]]
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[[Category: Polymorphism]]
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[[Category: Transport]]
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Current revision

Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.2 angstrom resolution

PDB ID 3d4x

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