1x6m

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[[Image:1x6m.png|left|200px]]
 
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==Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa)==
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The line below this paragraph, containing "STRUCTURE_1x6m", creates the "Structure Box" on the page.
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<StructureSection load='1x6m' size='340' side='right'caption='[[1x6m]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1x6m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X6M FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1x6m| PDB=1x6m | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x6m OCA], [https://pdbe.org/1x6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x6m RCSB], [https://www.ebi.ac.uk/pdbsum/1x6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x6m ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa)===
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== Function ==
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[https://www.uniprot.org/uniprot/GFA_PARDE GFA_PARDE] Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.<ref>PMID:11741920</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15548539}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15548539 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/1x6m_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15548539}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1x6m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X6M OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x6m ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:15548539</ref><ref group="xtra">PMID:11741920</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Paracoccus denitrificans]]
[[Category: Paracoccus denitrificans]]
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[[Category: Becker, S.]]
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[[Category: Becker S]]
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[[Category: Neculai, A M.]]
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[[Category: Neculai AM]]
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[[Category: Neculai, D.]]
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[[Category: Neculai D]]
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[[Category: Vorholt, J A.]]
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[[Category: Vorholt JA]]
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[[Category: 3_10 helix]]
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[[Category: Formaldehyde]]
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[[Category: Lyase]]
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[[Category: Zn-enzyme]]
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Current revision

Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa)

PDB ID 1x6m

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