2b5v

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[[Image:2b5v.png|left|200px]]
 
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==Crystal structure of glucose dehydrogenase from Haloferax mediterranei==
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The line below this paragraph, containing "STRUCTURE_2b5v", creates the "Structure Box" on the page.
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<StructureSection load='2b5v' size='340' side='right'caption='[[2b5v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2b5v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloferax_mediterranei Haloferax mediterranei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_2b5v| PDB=2b5v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5v OCA], [https://pdbe.org/2b5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5v RCSB], [https://www.ebi.ac.uk/pdbsum/2b5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5v ProSAT]</span></td></tr>
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</table>
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===Crystal structure of glucose dehydrogenase from Haloferax mediterranei===
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== Function ==
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[https://www.uniprot.org/uniprot/GLCDH_HALMT GLCDH_HALMT] Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate. Displays broad substrate specificity since it is able to catalyze the oxidation of a number of alternative aldose sugars, such as D-xylose, D-galactose, and D-fucose, to the corresponding glyconate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a preference for NADP(+). Physiologically, seems to be involved in the degradation of glucose through a modified Entner-Doudoroff pathway.<ref>PMID:11425479</ref> <ref>PMID:8925901</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16551747 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5v_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16551747}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2b5v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloferax_mediterranei Haloferax mediterranei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5V OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b5v ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:16551747</ref><ref group="xtra">PMID:11717506</ref><references group="xtra"/>
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<references/>
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[[Category: Glucose 1-dehydrogenase]]
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__TOC__
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</StructureSection>
[[Category: Haloferax mediterranei]]
[[Category: Haloferax mediterranei]]
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[[Category: Baker, P J.]]
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[[Category: Large Structures]]
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[[Category: Bonete, M J.]]
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[[Category: Baker PJ]]
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[[Category: Britton, K L.]]
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[[Category: Bonete M-J]]
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[[Category: Esclapez, J.]]
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[[Category: Britton KL]]
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[[Category: Ferrer, J.]]
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[[Category: Esclapez J]]
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[[Category: Fisher, M.]]
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[[Category: Ferrer J]]
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[[Category: Gilmour, D J.]]
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[[Category: Fisher M]]
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[[Category: Pire, C.]]
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[[Category: Gilmour DJ]]
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[[Category: Rice, D W.]]
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[[Category: Pire C]]
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[[Category: Ruzheinikov, S.]]
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[[Category: Rice DW]]
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[[Category: Nucleotide binding motif]]
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[[Category: Ruzheinikov S]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of glucose dehydrogenase from Haloferax mediterranei

PDB ID 2b5v

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