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1tg7

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[[Image:1tg7.png|left|200px]]
 
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==Native structure of beta-galactosidase from Penicillium sp.==
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The line below this paragraph, containing "STRUCTURE_1tg7", creates the "Structure Box" on the page.
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<StructureSection load='1tg7' size='340' side='right'caption='[[1tg7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_sp. Penicillium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TG7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1tg7| PDB=1tg7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tg7 OCA], [https://pdbe.org/1tg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1tg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tg7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BGALA_PENSQ BGALA_PENSQ] Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Has high in vitro transglycosylation activity with p-nitrophenyl-beta-D-galactopyranoside, methyl-beta-D-galactopyranoside or lactose as a donor and galactose as an acceptor.<ref>PMID:11053867</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tg/1tg7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tg7 ConSurf].
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<div style="clear:both"></div>
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===Native structure of beta-galactosidase from Penicillium sp.===
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==See Also==
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*[[Galactosidase 3D structures|Galactosidase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_15491613}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 15491613 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_15491613}}
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[[Category: Penicillium sp]]
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[[Category: Adamska M]]
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==About this Structure==
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[[Category: Arand M]]
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[[1tg7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Penicillium_sp. Penicillium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TG7 OCA].
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[[Category: Eneyskaya EV]]
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[[Category: Garratt RC]]
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==Reference==
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[[Category: Golubev AM]]
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<ref group="xtra">PMID:15491613</ref><references group="xtra"/>
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[[Category: Kulminskaya AA]]
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[[Category: Beta-galactosidase]]
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[[Category: Nagem RAP]]
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[[Category: Penicillium sp.]]
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[[Category: Neustroev KN]]
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[[Category: Adamska, M.]]
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[[Category: Polikarpov I]]
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[[Category: Arand, M.]]
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[[Category: Rojas AL]]
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[[Category: Eneyskaya, E V.]]
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[[Category: Garratt, R C.]]
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[[Category: Golubev, A M.]]
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[[Category: Kulminskaya, A A.]]
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[[Category: Nagem, R A.P.]]
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[[Category: Neustroev, K N.]]
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[[Category: Polikarpov, I.]]
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[[Category: Rojas, A L.]]
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Current revision

Native structure of beta-galactosidase from Penicillium sp.

PDB ID 1tg7

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