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1jzn
From Proteopedia
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| - | [[Image:1jzn.png|left|200px]] | ||
| - | + | ==crystal structure of a galactose-specific C-type lectin== | |
| - | + | <StructureSection load='1jzn' size='340' side='right'caption='[[1jzn]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1jzn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JZN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jzn OCA], [https://pdbe.org/1jzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jzn RCSB], [https://www.ebi.ac.uk/pdbsum/1jzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jzn ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/LECG_CROAT LECG_CROAT] Galactose-binding protein which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids. Calcium-dependent lectin. Shows high hemagglutinating activity (MHC is 10 ng/ml) (PubMed:1989986).<ref>PMID:1989986</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/1jzn_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | [[1jzn]] is a 5 chain structure with sequence from [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jzn ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | == | + | == References == |
| - | < | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Crotalus atrox]] | [[Category: Crotalus atrox]] | ||
| - | [[Category: Hirama | + | [[Category: Large Structures]] |
| - | [[Category: Nagar | + | [[Category: Hirama T]] |
| - | [[Category: Rini | + | [[Category: Nagar B]] |
| - | [[Category: Walker | + | [[Category: Rini JM]] |
| - | [[Category: Young | + | [[Category: Walker JR]] |
| + | [[Category: Young NM]] | ||
Current revision
crystal structure of a galactose-specific C-type lectin
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Categories: Crotalus atrox | Large Structures | Hirama T | Nagar B | Rini JM | Walker JR | Young NM

