3p23

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:37, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3p23.png|left|200px]]
 
-
<!--
+
==Crystal structure of the Human kinase and RNase domains in complex with ADP==
-
The line below this paragraph, containing "STRUCTURE_3p23", creates the "Structure Box" on the page.
+
<StructureSection load='3p23' size='340' side='right'caption='[[3p23]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3p23]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P23 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_3p23| PDB=3p23 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p23 OCA], [https://pdbe.org/3p23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p23 RCSB], [https://www.ebi.ac.uk/pdbsum/3p23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p23 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ERN1_HUMAN ERN1_HUMAN] Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.<ref>PMID:9637683</ref> <ref>PMID:11175748</ref> <ref>PMID:12637535</ref> [UniProtKB:Q9EQY0]
-
===Crystal structure of the Human kinase and RNase domains in complex with ADP===
+
==See Also==
-
 
+
*[[Ire1|Ire1]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21317875}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 21317875 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_21317875}}
+
-
 
+
-
==About this Structure==
+
-
[[3p23]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P23 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:21317875</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Ali, M M.U.]]
+
[[Category: Large Structures]]
-
[[Category: Pearl, L H.]]
+
[[Category: Ali MMU]]
 +
[[Category: Pearl LH]]

Current revision

Crystal structure of the Human kinase and RNase domains in complex with ADP

PDB ID 3p23

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3p23"
Personal tools