3o3m

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[[Image:3o3m.jpg|left|200px]]
 
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==(R)-2-Hydroxyisocaproyl-CoA Dehydratase==
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The line below this paragraph, containing "STRUCTURE_3o3m", creates the "Structure Box" on the page.
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<StructureSection load='3o3m' size='340' side='right'caption='[[3o3m]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3o3m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile Clostridioides difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O3M FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H2S:HYDROSULFURIC+ACID'>H2S</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3o3m| PDB=3o3m | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o3m OCA], [https://pdbe.org/3o3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o3m RCSB], [https://www.ebi.ac.uk/pdbsum/3o3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o3m ProSAT]</span></td></tr>
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</table>
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===(R)-2-Hydroxyisocaproyl-CoA Dehydratase===
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== Function ==
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[https://www.uniprot.org/uniprot/HADB_CLODI HADB_CLODI] Involved in the reductive branch of L-leucine fermentation. Catalyzes the irreversible beta/alpha-elimination of water from (R)-2-hydroxyisocaproyl-CoA to yield isocaprenoyl-CoA. This beta/alpha-dehydration depends on the reductive formation of ketyl radicals on the substrate generated by injection of a single electron from the ATP-dependent activator protein HadI. The enzyme is specific for the R-isomer.<ref>PMID:15654892</ref> <ref>PMID:21366233</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21366233 is the PubMed ID number.
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</StructureSection>
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[[Category: Clostridioides difficile]]
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{{ABSTRACT_PUBMED_21366233}}
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[[Category: Large Structures]]
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[[Category: Buckel W]]
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==About this Structure==
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[[Category: Dobbek H]]
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[[3o3m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_difficile Clostridium difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O3M OCA].
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[[Category: Knauer SH]]
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==Reference==
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<ref group="xtra">PMID:21366233</ref><references group="xtra"/>
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[[Category: Clostridium difficile]]
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[[Category: Buckel, W.]]
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[[Category: Dobbek, H.]]
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[[Category: Knauer, S H.]]
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Current revision

(R)-2-Hydroxyisocaproyl-CoA Dehydratase

PDB ID 3o3m

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