3r33
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3r33 is ON HOLD Authors: Collins, E.J., Lee, A.L., Carroll, M.J., Mauldin, R.V., Gromova, A.V., Singleton, S.F. Description: Evidence for dynamic m...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Evidence for dynamic motion in proteins as a mechanism for ligand dissociation== | |
| + | <StructureSection load='3r33' size='340' side='right'caption='[[3r33]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3r33]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R33 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ME:(6S)-6-METHYL-5,6,7,8-TETRAHYDROQUINAZOLINE-2,4-DIAMINE'>6ME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r33 OCA], [https://pdbe.org/3r33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r33 RCSB], [https://www.ebi.ac.uk/pdbsum/3r33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r33 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ||
| - | + | ==See Also== | |
| - | + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Carroll MJ]] | ||
| + | [[Category: Collins EJ]] | ||
| + | [[Category: Gromova AV]] | ||
| + | [[Category: Lee AL]] | ||
| + | [[Category: Mauldin RV]] | ||
| + | [[Category: Singleton SF]] | ||
Current revision
Evidence for dynamic motion in proteins as a mechanism for ligand dissociation
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