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3r55
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex of goat lactoperoxidase with Pyrazinamide at 2.1 A resolution== | |
| + | <StructureSection load='3r55' size='340' side='right'caption='[[3r55]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3r55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R55 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PZA:PYRAZINE-2-CARBOXAMIDE'>PZA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r55 OCA], [https://pdbe.org/3r55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r55 RCSB], [https://www.ebi.ac.uk/pdbsum/3r55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r55 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Lactoperoxidase|Lactoperoxidase]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Capra hircus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kaur P]] | ||
| + | [[Category: Pandey N]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Singh AK]] | ||
| + | [[Category: Singh RP]] | ||
| + | [[Category: Singh TP]] | ||
| + | [[Category: Sinha M]] | ||
Current revision
Crystal structure of the complex of goat lactoperoxidase with Pyrazinamide at 2.1 A resolution
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Categories: Capra hircus | Large Structures | Kaur P | Pandey N | Sharma S | Singh AK | Singh RP | Singh TP | Sinha M
