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3r6b
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3r6b is ON HOLD Authors: Page, R.C., Klenotic, P.A., Misra, S., Silverstein, R.L. Description: Crystal Structure of Thrombospondin-1 TSR Domains 2 ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3== | |
| + | <StructureSection load='3r6b' size='340' side='right'caption='[[3r6b]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3r6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R6B FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6b OCA], [https://pdbe.org/3r6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r6b RCSB], [https://www.ebi.ac.uk/pdbsum/3r6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r6b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSP1_HUMAN TSP1_HUMAN] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:11134179</ref> <ref>PMID:15014436</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Thrombospondin|Thrombospondin]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Klenotic PA]] | ||
| + | [[Category: Misra S]] | ||
| + | [[Category: Page RC]] | ||
| + | [[Category: Silverstein RL]] | ||
Current revision
Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
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