This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3r85

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3r85" [edit=sysop:move=sysop])
Current revision (12:13, 14 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 3r85 is ON HOLD
+
==Crystal structure of human SOUL BH3 domain in complex with Bcl-xL==
 +
<StructureSection load='3r85' size='340' side='right'caption='[[3r85]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3r85]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R85 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R85 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r85 OCA], [https://pdbe.org/3r85 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r85 RCSB], [https://www.ebi.ac.uk/pdbsum/3r85 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r85 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/B2CL1_HUMAN B2CL1_HUMAN] Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref> Isoform Bcl-X(S) promotes apoptosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref>
-
Authors: Ambrosi, E.K., Capaldi, S., Bovi, M., Saccomani, G., Perduca, M., Monaco, H.L.
+
==See Also==
-
 
+
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
-
Description: Crystal structure of human SOUL BH3 domain in complex with Bcl-xL
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Ambrosi EK]]
 +
[[Category: Bovi M]]
 +
[[Category: Capaldi S]]
 +
[[Category: Monaco HL]]
 +
[[Category: Perduca M]]
 +
[[Category: Saccomani G]]

Current revision

Crystal structure of human SOUL BH3 domain in complex with Bcl-xL

PDB ID 3r85

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3r85"
Personal tools