3izz

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[[Image:3izz.jpg|left|200px]]
 
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==Models for ribosome components that are nearest neighbors to the bovine mitochondrial initiation factor2 bound to the E. Coli ribosome==
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The line below this paragraph, containing "STRUCTURE_3izz", creates the "Structure Box" on the page.
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<SX load='3izz' size='340' side='right' viewer='molstar' caption='[[3izz]], [[Resolution|resolution]] 10.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3izz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3izz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izz OCA], [https://pdbe.org/3izz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3izz RCSB], [https://www.ebi.ac.uk/pdbsum/3izz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3izz ProSAT]</span></td></tr>
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{{STRUCTURE_3izz| PDB=3izz | SCENE= }}
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</table>
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== Function ==
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===Models for ribosome components that are nearest neighbors to the bovine mitochondrial initiation factor2 bound to the E. Coli ribosome===
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[https://www.uniprot.org/uniprot/RL14_ECOLI RL14_ECOLI] This protein binds directly to 23S ribosomal RNA. In the E.coli 70S ribosome (PubMed:12809609) it has been modeled to make two contacts with the 16S rRNA of the 30S subunit, forming part of bridges B5 and B8, connecting the 2 subunits. Although the protein undergoes significant rotation during the transition from an initiation to and EF-G bound state, the bridges remain stable. In the 3.5 A resolved structures (PubMed:16272117) L14 and L19 interact and together make contact with the 16S rRNA in bridges B5 and B8.<ref>PMID:22829778</ref> Can also interact with RsfA, in this case bridge B8 probably cannot form, and the 30S and 50S ribosomal subunits do not associate, which represses translation.<ref>PMID:22829778</ref>
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== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 21368145 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21368145}}
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==About this Structure==
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[[3izz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZZ OCA].
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==Reference==
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<ref group="xtra">PMID:21368145</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Agrawal, R K.]]
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[[Category: Large Structures]]
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[[Category: Banavali, N K.]]
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[[Category: Agrawal RK]]
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[[Category: Datta, P P.]]
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[[Category: Banavali NK]]
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[[Category: Elmore, K.]]
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[[Category: Datta PP]]
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[[Category: Haque, E.]]
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[[Category: Elmore K]]
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[[Category: Spremulli, L L.]]
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[[Category: Haque E]]
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[[Category: Yassin, A S.]]
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[[Category: Spremulli LL]]
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[[Category: Yassin AS]]

Current revision

Models for ribosome components that are nearest neighbors to the bovine mitochondrial initiation factor2 bound to the E. Coli ribosome

3izz, resolution 10.80Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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