3noi

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[[Image:3noi.jpg|left|200px]]
 
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==Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)==
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The line below this paragraph, containing "STRUCTURE_3noi", creates the "Structure Box" on the page.
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<StructureSection load='3noi' size='340' side='right'caption='[[3noi]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3noi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NOI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.842&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_3noi| PDB=3noi | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3noi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3noi OCA], [https://pdbe.org/3noi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3noi RCSB], [https://www.ebi.ac.uk/pdbsum/3noi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3noi ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)===
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== Function ==
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[https://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref>
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== References ==
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==About this Structure==
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<references/>
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[[3noi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOI OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Joyce, M G.]]
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[[Category: Large Structures]]
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[[Category: Sun, P D.]]
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[[Category: Joyce MG]]
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[[Category: Sun PD]]

Current revision

Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)

PDB ID 3noi

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