2cks

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[[Image:2cks.gif|left|200px]]<br /><applet load="2cks" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2cks, resolution 1.60&Aring;" />
 
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'''X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5)'''<br />
 
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==About this Structure==
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==X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5)==
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2CKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=BEN:'>BEN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] Known structural/functional Site: <scene name='pdbsite=AC1:Na Binding Site For Chain B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKS OCA].
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<StructureSection load='2cks' size='340' side='right'caption='[[2cks]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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[[Category: Cellulase]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2cks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CKS FirstGlance]. <br>
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[[Category: Thermobifida fusca]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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[[Category: Bergfors, T.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Berglund, G.I.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cks OCA], [https://pdbe.org/2cks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cks RCSB], [https://www.ebi.ac.uk/pdbsum/2cks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cks ProSAT]</span></td></tr>
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[[Category: Gross, L.S.]]
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</table>
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[[Category: Gualfetti, P.J.]]
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== Function ==
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[[Category: Mitchinson, C.]]
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[https://www.uniprot.org/uniprot/GUN5_THEFU GUN5_THEFU]
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[[Category: Requadt, C.]]
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== Evolutionary Conservation ==
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[[Category: Saldajeno, M.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Sandgren, M.]]
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Check<jmol>
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[[Category: Shaw, A.]]
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<jmolCheckbox>
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[[Category: BEN]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/2cks_consurf.spt"</scriptWhenChecked>
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[[Category: NA]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: ZN]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: carbohydrate metabolism]]
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</jmolCheckbox>
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[[Category: cellulose degradation]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cks ConSurf].
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[[Category: endoglucanase]]
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<div style="clear:both"></div>
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[[Category: glycosidase]]
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[[Category: glycoside hydrolase family 5]]
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[[Category: hydrolase]]
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[[Category: polysaccharide degradation]]
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[[Category: thermobifida fusca e5]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:05:37 2008''
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermobifida fusca]]
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[[Category: Bergfors T]]
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[[Category: Berglund GI]]
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[[Category: Gross LS]]
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[[Category: Gualfetti PJ]]
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[[Category: Mitchinson C]]
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[[Category: Requadt C]]
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[[Category: Saldajeno M]]
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[[Category: Sandgren M]]
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[[Category: Shaw A]]

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X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5)

PDB ID 2cks

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