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3rc0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3rc0 is ON HOLD Authors: Chang, Y., Levy, D., Horton, J.R., Peng, J., Zhang, X., Gozani, O., Cheng, X. Description: Human SETD6 in complex with Rel...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human SETD6 in complex with RelA Lys310 peptide== | |
| + | <StructureSection load='3rc0' size='340' side='right'caption='[[3rc0]], [[Resolution|resolution]] 2.19Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RC0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rc0 OCA], [https://pdbe.org/3rc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3rc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rc0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SETD6_HUMAN SETD6_HUMAN] Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.<ref>PMID:21131967</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chang Y]] | ||
| + | [[Category: Cheng X]] | ||
| + | [[Category: Gozani O]] | ||
| + | [[Category: Horton JR]] | ||
| + | [[Category: Levy D]] | ||
| + | [[Category: Peng J]] | ||
| + | [[Category: Zhang X]] | ||
Current revision
Human SETD6 in complex with RelA Lys310 peptide
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Categories: Homo sapiens | Large Structures | Chang Y | Cheng X | Gozani O | Horton JR | Levy D | Peng J | Zhang X
